Author's response to reviews Title: Transcript levels of Toll-like receptors 5, 8 and 9 correlate with inflammatory activity in Ulcerative Colitis Authors:

Transcript levels of Toll-Like receptors 5, 8 and 9 correlate with inflammatory activity in Ulcerative Colitis

BACKGROUND Dysregulation of innate immune response by Toll-Like Receptors (TLRs) is a key feature in Ulcerative Colitis (UC). Most studies have focused on TLR2, TLR3, and TLR4 participation in UC. However, few studies have explored other TLRs. Therefore, the aim of this study was to evaluate the mRNA profiles of TLR1 to 9 in colonic mucosa of UC patients, according to disease activity. METHOD...

Interleukin-17 Serum Levels and TLR4 Polymorphisms in Ulcerative Colitis

Background: Inflammatory bowel disease, an autoimmune disease, has two clinical manifestations including Crohn’s disease and ulcerative colitis (UC). IL-17 has been the target of intensive research in autoimmune diseases. The influence of Toll like receptor 4 (TLR-4) gene polymorphisms on IL-17 production has also been revealed in UC patients and tissue inflammation in mice. Objectives: To inve...

Author's response to reviews Title: Comparative analysis of inflamed and non-inflamed colon biopsies reveals strong proteomic inflammation profile in patients with ulcerative colitis Authors:

Title: Comparative analysis of inflamed and non-inflamed colon biopsies reveals strong proteomic inflammation profile in patients with ulcerative colitis

Author's response to reviews Title: Toll-Like Receptor Gene Polymorphisms are Associated with Susceptibility to Graves' Ophthalmopathy in Taiwan Males Authors:

Author's response to reviews Title: Toll-like receptor 9 polymorphisms are associated with severity variables in a cohort of meningococcal meningitis survivors Authors: